Drug Standards
Advanced Chemblocks Inc Afatinib; 100MG; 98%
Chemical Name: Afatinib CAS: 850140-72-6 MW: 485.95 MDL Number: MFCD12407405 Category: Reference Compound Synonym: Afatinib
Selleck Chemical LLC Protionamide 50mg 14222-60-7 Prothionamide, 1321-TH
Protionamide (Prothionamide, 1321-TH) is a drug used in the treatment of tuberculosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Atovaquone | 95233-18-4 | 99.8% | 366.84 | 100 MG
Atovaquone is a potent, selective, and orally active inhibitor of the parasite's mitochondrial cytochrome bc1 complex. It is an antimalarial agent with potential for investigating pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
- Potent, selective, and orally active inhibitor of the parasite's mitochondrial cytochrome bc1 complex.
- Effective against human and P. falciparum cytochrome bc1 activity.
- Active against development in the mosquito from gamete production to ookinete.
- Potential for investigating pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
Apexbio Technology LLC Tofacitinib (CP-690550,Tasocitinib) 477600-75-2 50mg
Tofacitinib (CP-690550 Tasocitinib CAS 477600-75-2) is an orally bioavailable Janus kinase (JAK) inhibitor employed as a targeted immunomodulator The compound preferentially inhibits signaling mediated by JAK1 and JAK3 heterodimers displaying functional selectivity and less pronounced effects on JAK2 pathways Such inhibition disrupts downstream cytokine signaling notably IL-2 IL-4 IL-7 IL-9 IL-15 and IL-21 cytokines implicated in lymphocyte activation proliferation and differentiation Recent studies also indicate suppression of STAT signaling and potential modulation of additional kinase targets Tofacitinib is broadly studied in autoimmune research especially in rheumatoid arthritis and ulcerative colitis models
Medchemexpress LLC Aminopterin (4-aminofolic acid) | 54-62-6 | 98.7% | C19H20N8O5 | 100 MG
Aminopterin (4-Aminofolic acid) is a 4-amino derivative of folic acid and acts as a folic acid antagonist. It catalyzes the reduction of folic acid to tetrahydrofolic acid and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. This compound exhibits anticancer and immunosuppressive activities and is utilized in the treatment of pediatric leukemia.
- Folic acid antagonist
- Catalyzes reduction of folic acid to tetrahydrofolic acid
- Competitively inhibits dihydrofolate reductase (DHFR)
- Anticancer activity
- Immunosuppressive activity
- Used in the treatment of pediatric leukemia
Medchemexpress LLC Octyl gallate | 1034-01-1 | 282.33 | 100 MG
Octyl gallate (Progallin O) is widely used as a food additive with antimicrobial and antioxidant activity. It also shows selective and sensitive fluorescent properties and has a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV), and poliovirus. It also exhibits antimicrobial activity over H. pylori, with a minimum inhibitory concentration (MIC) value of 125 μg/mL.
- Widely used as a food additive.
- Exhibits antimicrobial and antioxidant activity.
- Shows selective and sensitive fluorescent properties.
- Possesses marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV), and poliovirus.
- Demonstrates antimicrobial activity over H. pylori, with a minimum inhibitory concentration (MIC) value of 125 μg/mL.
Medchemexpress LLC Avotaciclib (trihydrochloride) | 1983984-01-5 | 99.6% | 390.66 | 1 MG
Avotaciclib trihydrochloride is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. It can inhibit the proliferation and induce apoptosis of tumor cells. This product is used in the research of cancers such as pancreatic cancer and lung cancer.
- Inhibits cell proliferation and promotes apoptosis in radiotherapy-resistant non-small cell lung cancer cell lines.
- Demonstrates enhanced efficacy when used in combination with certain other compounds.
- Applicable in cancer research, including studies on pancreatic and lung cancer.
![eMolecules 20442-70-0 | Cesium Pivalate | Accela ChemBio (ASD) | MFCD10567040 | 234.030 | C5H9CsO2 | 97.000 | [Cs+].CC(C)(C)C([O-])=O | 5g | 596321416](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000472933.jpg-250.jpg)
eMolecules 20442-70-0 | Cesium Pivalate | Accela ChemBio (ASD) | MFCD10567040 | 234.030 | C5H9CsO2 | 97.000 | [Cs+].CC(C)(C)C([O-])=O | 5g | 596321416
Cesium Pivalate | Accela ChemBio (ASD) | 20442-70-0 | MFCD10567040 | 234.030 | C5H9CsO2 | 97.000 | [Cs+].CC(C)(C)C([O-])=O | 5g | 596321416
Medchemexpress LLC (3S,4S)-Tivantinib | 905854-03-7 | C23H19N3O2 | 500 MG
(3S,4S)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. It also targets GSK3α and GSK3β, which are important in the cellular mechanism of non-small cell lung cancer (NSCLC).
- Potent and highly selective inhibitor of the receptor tyrosine kinase c-MET
- Targets GSK3α and GSK3β
- Important in the cellular mechanism of non-small cell lung cancer (NSCLC)
Cayman Chemical 1R-Camphor 500mg
A terpene with diverse biological activities; it inhibits DMPP-induced norepinephrine secretion and cytosolic calcium and sodium increases in chromaffin cells (IC50s = 70, 88, and 19 μM, respectively); induces proliferation of and increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in human primary dermal fibroblasts from 65-260 μM; increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in skin in UV-exposed mice at 26 and 55 mM in drinking water post UV-exposure; reduces cough frequency in citric acid-challenged guinea pigs; reduces digging activity and induces mortality in fire ant workers; has been used as a building block in the synthesis of cannabinergic ligands
TARGETMOL CHEMICALS INC LATANOPROST 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Latanoprost (Xalatan) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. purity: 99%
![Medchemexpress LLC Ethyl 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-tetrahydrothiazolo[5,4-c]pyridine-2-...) | 480450-85-9 | MFCD30489921 | 50mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000266448.png-250.jpg)
Medchemexpress LLC Ethyl 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-tetrahydrothiazolo[5,4-c]pyridine-2-...) | 480450-85-9 | MFCD30489921 | 50mg
Edoxaban Impurity 49 is an impurity of Edoxaban (HY-10264)
Sigma Aldrich Fine Chemicals Biosciences SILuTMMAb Nivolumab Stable
SILu(TM)MAb Nivolumab (MSQC27) is a recombinant stable isotope-labeled monoclonal antibody which incorporates [13C6 15N4]-Arginine and [13C6 15N2]-Lysine. Expressed in CHO cells it is designed to be used as an internal standard for the quantitative mass spectrometry analysis of Nivolumab in human and animal serum. SILu(TM)MAb Nivolumab is for research use only and is not intended for diagnostic or therapeutic use.
Medchemexpress LLC Cabamiquine succinate | 2444781-71-7 | 99.8% | 580.65 | C31H37FN4O6 | 100 MG
Cabamiquine succinate is the succinate salt of cabamiquine (DDD107498), a potent orally active antimalarial that inhibits Plasmodium protein synthesis by targeting the parasite elongation factor eEF2. It exhibits low-nanomolar cellular potency and is provided for research use under controlled storage conditions.
- Potent antimalarial activity against Plasmodium species.
- Targets parasite elongation factor eEF2 to inhibit protein synthesis.
- Low-nanomolar potency in cellular assays.
- High chemical purity appropriate for research applications.
- Stable when stored sealed away from moisture and light.
Cayman Chemical Reduced HaloperIdol 50mg
An active metabolite of haloperidol; formed via reduction of haloperidol by ketone reductase; inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively); stimulates BDNF secretion from CCF-SSTG1 and U87MG astrocytic glial cells; inhibits norepinephrine, dopamine, and 5-HT reuptake (Kis = 21, 25, and 33 μM, respectively, in COS-7 cells expressing the human transporters); increases latency to paw withdrawal in mouse models of capsaicin-induced mechanical hypersensitivity at 0.5 mg/kg